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home.gifWelcome to EUROMYASTHENIA [ ]

The objective of this site is to disseminate research results from the European project EuroMyasthenia and to encourage communication on the rare disease, Myasthenia Gravis. In order to identify the partners involved, please click on the map.

To get information about the project and the network activities, please click on the titles in the Informations and Scientific activities side-boxes.

To get advices about Myasthenia Gravis in your country, please visit the FAQ section.

MG researchers need your help!

MG researchers need your help in locating identical twin pairs where one or both of the twins are affected with MG, to carry out a study of the contribution of environmental and genetic factors to MG. As you know, both MG and identical twins are rare, so any such subjects are especially precious. For further information, read more

Click on the map to locate partners

news.gifThe 3 last news

COMING SOON - by Jacky Bismuth (Public Euromyasthenia Website) 17/02/2012 - 1:21 PM

Coming soon: The New york academy of sciences and the Myasthenia Gravis Foundation of America are organizing the 12th international conference on Myasthenia Gravis, which will be held on 21-23 may 2012 at New-York, USA.

The deadline to post your abstract is the 23rd of March.

The FIGHT-MG project - by Jacky Bismuth (Public Euromyasthenia Website) 22/12/2010 - 3:40 PM

FIGHT-MG is a European consortium including 12 scientific teams from 7 different countries (France, Germany, Greece, Israel, Italy, Norway, Switzerland). This project focused on Myasthenia Gravis disease aims to shed light on the course, etiological and pathological mechanisms and to develop new diagnostic and therapy tools.

Myasthenia Gravis (MG) is a heterogeneous rare autoimmune neurological disease affecting the neuromuscular junction (NMJ). The molecular events causing and maintaining MG are still unknown and current treatments do not lead to remission and entail considerable side-effects stressing the need for improved therapies.

The FIGHT-MG project aims to:

1. Determine factors associated with disease onset and/or affecting the course of the disease.
2. Identify new genetic, epigenetic and environmental risk factors and investigate immunological key molecules associated with MG onset.
3. Study the pathogenic mechanisms at the neuromuscular junction (molecular and morphological changes)
4. Establish new diagnostic and monitoring assays, by identifying pathogenic and protective factors, improving the sensitivity of current assays and discovering new biomarkers
5. Establish novel therapies by targeting several levels of the pathogenic response.

This multidisciplinary project linking basic researchers with clinical neurologists, SMEs and several European patient associations should favor a translational approach for improved MG management.

The scientific coordination is under the responsibility of S. Berrih-Aknin, DSc (Institute of Myology) and the project is managed by Inserm-Transfert.


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